EGFR突变肺鳞癌与结局关联表4

数据集获取（Figshare）

• 源站标题：Table_4_EGFR-Mutated Squamous Cell Lung Cancer and Its Association With Outcomes.docx
• DOI：10.3389/fonc.2021.680804.s006
• 发布日期：2021-06-14
• 文件数：1 个
• 文件总体积：19.08 KB
• 源站页面：https://frontiersin.figshare.com/articles/dataset/Table_4_EGFR-Mutated_Squamous_Cell_Lung_Cancer_and_Its_Association_With_Outcomes_docx/14777484

命令行下载

curl -L -o "Table_4_EGFR-Mutated Squamous Cell Lung Cancer and Its Association With Outcomes.docx" "https://ndownloader.figshare.com/files/28396608"

文件清单

• Table_4_EGFR-Mutated Squamous Cell Lung Cancer and Its Association With Outcomes.docx（19.08 KB）

文件总体积 19.08 KB（源站 API 实测）。

数据加载示例（图像类）

from PIL import Image
import glob, os

files = (glob.glob(os.path.join(path, "**", "*.png"), recursive=True)
       + glob.glob(os.path.join(path, "**", "*.jpg"), recursive=True)
       + glob.glob(os.path.join(path, "**", "*.tif"), recursive=True))
print("图像文件数:", len(files))
img = Image.open(files[0]); print("尺寸/模式:", img.size, img.mode)

# torchvision Dataset 方式:
# from torchvision import datasets
# ds = datasets.ImageFolder(path)  # 要求 子目录=类别

目录组织与标注格式以源站说明和下载后实际文件为准。

数据说明

BackgroundThe therapeutic efficacy of epidermal growth factor receptor tyrosine kinase inhibitors (EGFR-TKIs) in advanced EGFR-mutant lung squamous cell carcinoma (SCC) patients remains uncertain. Furthermore, the factors underlying the responsiveness have not been fully investigated. We therefore investigated the link between genomic profiles and EGFR-TKI efficacy.
Material and MethodsWe consecutively enrolled stage IV, EGFR-mutant, and EGFR-TKI–treated patients with SCC. Patients with EGFR wild-type lung SCC and EGFR-mutant lung adenocarcinoma were consecutively enrolled as controls, and next-generation sequencing (NGS) was performed.
ResultsIn total, 28 EGFR-mutant lung SCC, 41 EGFR-mutant lung adenocarcinoma, and 40 EGFR wild-type lung SCC patients were included. Among the patients with EGFR mutations, shorter progression-free survival (PFS) was observed in SCC compared to adenocarcinoma (4.6 vs. 11.0 months, PEGFR-mutant lung SCC has a worse prognosis than EGFR-mutant adenocarcinoma. Mutations in other genes, such as CREBBP, ZNF217, GRM8, or Wnt that had implications on PFS raise the possibility of understanding mechanisms of resistance to EGFR-TKI in lung SCC, which will aid identification of potential beneficial subgroups of patients with EGFR-mutant SCCs receiving EGFR-TKIs.

许可

CC BY 4.0

引用

学术使用请引用 DOI 10.3389/fonc.2021.680804.s006（source: https://frontiersin.figshare.com/articles/dataset/Table_4_EGFR-Mutated_Squamous_Cell_Lung_Cancer_and_Its_Association_With_Outcomes_docx/14777484）。