血液肿瘤/疾病中的非清髓性异基因造血细胞移植
该数据集来自 clinicaltrials.gov,聚焦血液系统恶性肿瘤或再生障碍性贫血患者接受非清髓性异基因外周血干细胞移植的研究

基本信息
资源简介
血液肿瘤/疾病中的非清髓性异基因造血细胞移植
该数据集来自 clinicaltrials.gov,聚焦血液系统恶性肿瘤或再生障碍性贫血患者接受非清髓性异基因外周血干细胞移植的研究。覆盖慢性骨髓增殖性疾病、白血病、淋巴瘤、多发性骨髓瘤与浆细胞肿瘤、骨髓增生异常综合征、骨髓增生异常/骨髓增殖性疾病、范可尼贫血及再生障碍性贫血。数据可用于评估移植方案的安全性、毒性反应、临床应答与总体结局,以及移植物抗肿瘤效应、移植物抗宿主病和嵌合状态的发生情况,为血液肿瘤移植研究提供参考(来源 clinicaltrials.gov)。
【数据内容】
源站描述(机器翻译,仅供参考):疾病:慢性骨髓增殖性疾病、白血病、淋巴瘤、多发性骨髓瘤与浆细胞肿瘤、骨髓增生异常综合征、骨髓增生异常/骨髓增殖性疾病、范可尼贫血、再生障碍性贫血。目的: 确定非清髓性异基因外周血干细胞移植在血液系统恶性肿瘤或再生障碍性贫血患者中的安全性和毒性反应。 确定接受该方案治疗患者的临床应答和总体结局。 确定接受该方案治疗患者中移植物抗肿瘤效应、移植物抗宿主病和嵌合状态的发生率。方案概要: 预处理方案: 配型相合同胞和非血缘供者移植: 患者在第-5天和第-4天接受环磷酰胺静脉注射2小时以上,并在第-5天至第-1天接受氟达拉滨静脉注射30分钟以上。 脐带血移植: 患者接受相同方案
【主题与分类】
主题标签:Chronic Myeloproliferative Disorders、Leukemia、Lymphoma、Myelodysplastic Syndromes、Fanconi Anemia、Aplastic Anemia。本站分类:肿瘤/白血病。
【获取与许可】
源站页面:https://clinicaltrials.gov/study/NCT00053989
下载信息
注册下载
需要注册 Kaggle 账号并登录后下载,适合需要跟踪下载记录和使用 API 的用户。
暂未开放公开下载
无需注册即可直接获取公开样本或文档,适合快速预览和评估数据集质量。
免登录有偿下载
公开数据集受托下载与技术交付服务。
提供高速下载与技术交付服务(收技术服务费,非数据销售)
暂未开放当前数据集主要来源为 Kaggle 公开托管,完整影像包建议通过原始链接或 Kaggle API 获取。
使用方式
数据集获取
源站:https://clinicaltrials.gov/study/NCT00053989
标准获取流程:
- 访问源站链接,注册/登录账号;
- 进入数据集详情页,按页面指引申请权限或直接下载;
- 部分平台提供 SDK,例如:
- OpenDataLab:
pip install openxlab后openxlab.dataset.get(...) - ModelScope:
pip install modelscope后modelscope download - 天池: 登录后页面提供直链下载
以源站「数据下载/使用文档」页面为准。
- OpenDataLab:
数据说明
Conditions: Chronic Myeloproliferative Disorders, Leukemia, Lymphoma, Multiple Myeloma and Plasma Cell Neoplasm, Myelodysplastic Syndromes, Myelodysplastic/Myeloproliferative Diseases, Fanconi Anemia, Aplastic Anemia. OBJECTIVES: * Determine the safety and toxic effects of nonmyeloablative allogeneic peripheral blood stem cell transplantation in patients with a hematologic malignancy or aplastic anemia. * Determine clinical response and overall outcome of patients treated with this regimen. * Determine the incidence of graft-vs-tumor effect, graft-vs-host disease, and chimerism in patients treated with this regimen. OUTLINE: * Preparative regimen: * Matched related and unrelated donor transplantation: * Patients receive cyclophosphamide IV over 2 hours on days -5 and -4 and fludarabine IV over 30 minutes on days -5 to -1. * Cord blood transplantation: * Patients receive the same regimen as above plus anti-thymocyte globulin IV over 4 hours on days -3 to -1. * Graft-vs-host disease (GVHD) prophylaxis: * Matched related and unrelated donor transplantation: * Patients receive oral tacrolimus (or IV) once daily and oral mycophenolate mofetil (MMF) (or IV) twice daily on days -1 to 60 followed by tapering* of this regimen. Patients then receive methotrexate IV on days 1, 3, and 6. * Cord blood transplantation: * Patients receive tacrolimus and MMF in the same regimen as above plus methylprednisolone twice daily on days 1-19 or until blood counts recover. * Allogeneic stem cell reinfusion: Patients undergo allogeneic bone marrow or peripheral blood stem cell transplantation on day 0. Patients then receive sargramostim (GM-CSF) subcutaneously daily beginning on day 7 and continuing until blood counts recover. * Donor lymphocyte infusion (DLI): Patients not converting to 100% donor T-cell chimerism by day 120 and showing signs of progresson of disease after tacrolimus and MMF withdrawal may receive DLI every 8 weeks for up to 3 infusions. Cord blood recipients do not receive DLI. Patients are followed at day 100-120, every 3 months for 2 years, and then every 6 months for 5 years. PROJECTED ACCRUAL: A total of 30-60 patients will be accrued for this study within 6-7 yea
数据加载示例(图像类)
from PIL import Image
import glob, os
files = (glob.glob(os.path.join(path, "**", "*.png"), recursive=True)
+ glob.glob(os.path.join(path, "**", "*.jpg"), recursive=True)
+ glob.glob(os.path.join(path, "**", "*.tif"), recursive=True))
print("图像文件数:", len(files))
img = Image.open(files[0]); print("尺寸/模式:", img.size, img.mode)
# torchvision Dataset 方式:
# from torchvision import datasets
# ds = datasets.ImageFolder(path) # 要求 子目录=类别
目录组织与标注格式以源站说明和下载后实际文件为准。
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