Data Sheet 1_Real-world challenges in hepatocellular carcinoma in Central America and the Caribbean: insights from a multinational expert survey.pdf

Data Sheet 1_Real-world challenges in hepatocellular carcinoma in Central America and the Caribbean: insights from a multinational expert survey.pdf [Background] Companion paper: "Real-world challenges in hepatocellular carcinoma in Central America and the Caribbean: insights from a multinational expert survey", Frontiers in Oncology (2025), DOI: 10.3389/fonc.2025.1671564. First published on 2025-10-20. [Content] Hepatocellular carcinoma (HCC) represents a growing public health concern in Central America and the Caribbean, yet regional data on its management remain limited. A cross-sectional descriptive survey was conducted among 51 liver cancer specialists across nine countries, exploring four domains: epidemiology, screening, diagnostics, and treatment access. Analysis of the 20-item questionnaire revealed significant disparities in HCC care across the region. National cancer registries and structured screening programs were largely absent. Although ultrasound was widely available, its routine use for surveillance was inconsistent, and radiologist training levels varied. Access to diagnostic imaging such as triphasic computed tomography and magnetic resonance imaging was uneven. While liver surgery was generally accessible, liver transplantation was limited to Costa Rica and, to a lesser extent, the Dominican Republic. Systemic therapies such as sorafenib and lenvatinib were commonly available, However, access to first-line immunotherapy was constrained by limited insurance coverage and delayed governmental approval. In several countries, fewer than 30% of patients received treatment approval, with delays exceeding five months. Multidisciplinary tumor boards were not routinely implemented. In conclusion, these findings provide the first regional overview of HCC management in Central America and the Caribbean, underscoring critical gaps in surveillance infrastructure, diagnostic capacity, therapeutic access, and institutional coordination. Addressing these gaps is essential to improving liver cancer outcomes and equity across the region. [Structure and specifications] 1 file(s), 123.86 KB in total. Dataset DOI: 10.3389/fonc.2025.1671564.s001. [Topics] Subject categories: Oncology and Carcinogenesis not elsewhere classified. Tags: hepatocellular carcinoma, liver cancer epidemiology, cancer screening and surveillance, cancer diagnosis and imaging, liver cancer landscape, cancer epidemiology and prevention, immunotherapy in oncology. [Intended use] Textual data supports medical NLP tasks such as named entity recognition, information extraction and text classification. [Access and licence] Source page: https://frontiersin.figshare.com/articles/dataset/Data_Sheet_1_Real-world_challenges_in_hepatocellular_carcinoma_in_Central_America_and_the_Caribbean_insights_from_a_multinational_expert_survey_pdf/30397612 License: CC BY 4.0. Please cite as: Perelló, Christie; Disla, Hugo J.; Coste, Pablo; Valdez, Marisabell; Páez, Dayron; Rivera, Carlos; et al. (2025). Data Sheet 1_Real-world challenges in hepatocellular carcinoma in Central America and the Caribbean: insights from a multinational expert survey.pdf. Frontiers. Dataset