中国食管癌精准筛查成本效益数据集（ESECC试验）

数据集获取（Figshare）

• 源站标题：DataSheet_1_Cost-effectiveness of precision screening for esophageal cancer based on individualized risk stratification in China: Real-world evidence from the ESECC trial.docx
• DOI：10.3389/fonc.2022.1002693.s001
• 发布日期：2022-11-30
• 文件数：1 个
• 文件总体积：119.51 KB
• 源站页面：https://frontiersin.figshare.com/articles/dataset/DataSheet_1_Cost-effectiveness_of_precision_screening_for_esophageal_cancer_based_on_individualized_risk_stratification_in_China_Real-world_evidence_from_the_ESECC_trial_docx/21646394

命令行下载

curl -L -o "DataSheet_1_Cost-effectiveness of precision screening for esophageal cancer based on individualized risk stratification in China: Real-world evidence .docx" "https://ndownloader.figshare.com/files/38377658"

文件清单

• DataSheet_1_Cost-effectiveness of precision screening for esophageal cancer based on individualized risk stratification in China: Real-world evidence .docx（119.51 KB）

文件总体积 119.51 KB（源站 API 实测）。

数据加载示例（图像类）

from PIL import Image
import glob, os

files = (glob.glob(os.path.join(path, "**", "*.png"), recursive=True)
       + glob.glob(os.path.join(path, "**", "*.jpg"), recursive=True)
       + glob.glob(os.path.join(path, "**", "*.tif"), recursive=True))
print("图像文件数:", len(files))
img = Image.open(files[0]); print("尺寸/模式:", img.size, img.mode)

# torchvision Dataset 方式:
# from torchvision import datasets
# ds = datasets.ImageFolder(path)  # 要求 子目录=类别

目录组织与标注格式以源站说明和下载后实际文件为准。

数据说明

BackgroundConventional universal endoscopic screening with pathology-based endoscopic re-examination for esophageal squamous cell carcinoma is in need of reform in China. We established a “two-step” precision screening strategy using two risk prediction models and have evaluated the cost-effectiveness of this precision strategy compared with the traditional strategy based on a large population-level randomized controlled trial from a healthcare provider’s perspective.
MethodsFour precision screening strategies with different risk cutoffs at baseline screening and endoscopic surveillance were constructed, and then compared with traditional strategy through modeling using subjects from the screening cohort of the ESECC (Endoscopic Screening for Esophageal Cancer in China) trial. Total screening costs and the number of SDA (severe dysplasia and above in lesions of the esophagus) cases were obtained to calculate the average screening cost per SDA detected, the incremental cost-effectiveness ratio (ICER) and protection rates. Sensitivity analysis was conducted to evaluate uncertainties.
ResultsCompared to traditional strategy, all precision screening strategies have much lower average costs for detection of one SDA case ($7,148~$11,537 vs. $14,944). In addition, precision strategies 1&2 (strategies 1,2,3,4 described below) achieved higher effectiveness (143~150 vs. 136) and higher protection rates (87.7%~92.0% vs. 83.4%) at lower cost ($1,649,727~$1,672,221 vs. $2,032,386), generating negative ICERs (-$54,666/SDA~-$25,726/SDA) when compared to the traditional strategy. The optimal strategies within different willingness-to-pay (WTP) ranges were all precision screening strategies, and higher model sensitivities were adopted as WTP increased.
ConclusionsPrecision screening strategy for esophageal cancer based on risk stratification is more cost-effective than use of traditional screening strategy and has practical implications for esophageal cancer screening programs in China.

许可

CC BY 4.0

引用

学术使用请引用 DOI 10.3389/fonc.2022.1002693.s001（source: https://frontiersin.figshare.com/articles/dataset/DataSheet_1_Cost-effectiveness_of_precision_screening_for_esophageal_cancer_based_on_individualized_risk_stratification_in_China_Real-world_evidence_from_the_ESECC_trial_docx/21646394）。