开放儿童脑肿瘤图谱
肿瘤领域表格公开数据集，来源：OpenPBTA。
基本信息
资源简介
开放儿童脑肿瘤图谱
【数据集背景】
本数据集源站标题为《AlexsLemonade/OpenPBTA-analysis》。源站首次发布：2019-06-18。
【数据内容】
源站原始描述：The analysis repository for the Open Pediatric Brain Tumor Atlas Project # OpenPBTA-analysis - **OpenPBTA is now published**: Shapiro, J.A., Gaonkar, K.S., Spielman, S.J., Savonen, C.L., Bethell, C.J., Jin, R., Rathi, K.S., Zhu, Y., Egolf, L.E., Farrow, B.K., et al. (2023). OpenPBTA: The Open Pediatric Brain Tumor Atlas. Cell Genom., 100340. 10.1016/j.xgen.2023.100340. **We will no longer be accepting contributions to this repository.** Please check out `d3b-center/OpenPedCan-analysis` for upd…
【适用方向】
结构化表格数据可直接用于统计建模、特征工程与队列分析。
【获取与许可】
源站页面：https://github.com/AlexsLemonade/OpenPBTA-analysis
使用许可：NOASSERTION。
【使用注意】
· 源站最后修改于 2023-06-21，引用时请注意版本时效。
下载信息
注册下载
需要注册 Kaggle 账号并登录后下载，适合需要跟踪下载记录和使用 API 的用户。
暂未开放公开下载
无需注册即可直接获取公开样本或文档，适合快速预览和评估数据集质量。
免登录有偿下载
公开数据集受托下载与技术交付服务。
提供高速下载与技术交付服务（收技术服务费，非数据销售）
暂未开放当前数据集主要来源为 Kaggle 公开托管，完整影像包建议通过原始链接或 Kaggle API 获取。
使用方式
数据集获取
git clone https://github.com/AlexsLemonade/OpenPBTA-analysis.git
curl -L -o repo.zip https://github.com/AlexsLemonade/OpenPBTA-analysis/archive/refs/heads/master.zip
unzip repo.zip
源站 README 摘录（使用方式）
OpenPBTA-analysis
OpenPBTA is now published:
Shapiro, J.A., Gaonkar, K.S., Spielman, S.J., Savonen, C.L., Bethell, C.J., Jin, R., Rathi, K.S., Zhu, Y., Egolf, L.E., Farrow, B.K., et al. (2023). OpenPBTA: The Open Pediatric Brain Tumor Atlas. Cell Genom., 100340. 10.1016/j.xgen.2023.100340.
We will no longer be accepting contributions to this repository.
Please check out d3b-center/OpenPedCan-analysis for updates to PBTA data as well as other data sources.
Pediatric brain tumors are the most common solid tumors and the leading cause of cancer-related death in children.
Our ability to understand and successfully treat these diseases is hindered by small sample sizes due to the overall rarity of unique molecular subtypes and tainted grouped analyses resulting from misclassification.
In September of 2018, the Children’'s Brain Tumor Network (CBTN) released the Pediatric Brain Tumor Atlas (PBTA), a genomic dataset (whole genome sequencing, whole exome sequencing, RNA sequencing, proteomic, and clinical data) for nearly 1,000 tumors, available from the Gabriella Miller Kids First Portal.
The Open Pediatric Brain Tumor Atlas (OpenPBTA) Project is a global open science initiative to comprehensively define the molecular landscape of tumors of 943 patients from the CBTN and the PNOC003 DIPG clinical trial from the Pediatric Pacific Neuro-oncology Consortium through real-time, collaborative analyses and collaborative manuscript writing on GitHub.
The OpenPBTA operates on a pull request model to accept contributions from community participants.
The maintainers have set up continuous integration software to confirm the reproducibility of analyses within the project’s Docker container.
The collaborative manuscript is authored using Manubot software to provide an up-to-date public version of the manuscript.
The project maintainers include scientists from Alex’‘s Lemonade Stand Foundation’'s Childhood Cancer Data Lab and the [Center for Data-Driven Discovery in Biomedicine at the Children’'s Hospital of Philadelphia](https://d3b.cent
数据加载示例（表格/文本类）
import pandas as pd, glob, os
files = (glob.glob(os.path.join(path, "**", "*.csv"), recursive=True)
+ glob.glob(os.path.join(path, "**", "*.tsv"), recursive=True)
+ glob.glob(os.path.join(path, "**", "*.xlsx"), recursive=True))
print("数据文件:", files)
df = pd.read_csv(files[0])
print(df.shape); print(df.columns.tolist()); print(df.head(3))
数据缺失？
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