PD-L1和IDO1是中枢神经系统原发弥漫大B细胞淋巴瘤患者治疗的潜在靶点

资源简介

PD-L1和IDO1是中枢神经系统原发弥漫大B细胞淋巴瘤患者治疗的潜在靶点

【数据集背景】

本数据集源站标题为《PD-L1 and IDO1 are potential targets for treatment in patients with primary diffuse large B-cell lymphoma of the CNS》。配套论文《PD-L1 and IDO1 are potential targets for treatment in patients with primary diffuse large B-cell lymphoma of the CNS》发表于 Acta Oncologica（2021），DOI：10.1080/0284186X.2021.1881161。项目资助方：The authors acknowledge the support from the National Genomics Infrastructure funded by the Science for Life Laboratory, the Knut and Alice Wallenberg Foundation and the Swedish Research Council. This work was supported by grants from the Swedish Cancer Society, Uppsala University Hospital ALF grant, the Lions Cancer Foundation in Uppsala, Akademiska Sjukhuset and Cancerfonden. All authors have declared no financial conflict of interest in regard to this work.。源站首次发布：2021-02-13。

【数据内容】

源站原始描述：Programmed cell death 1 (PD-1) and its ligands PD-L1 and PD-L2, as well as Indoleamine 2,3-deoxygenase (IDO1) can be expressed both by tumor and microenvironmental cells and are crucial for tumor immune escape. We aimed to evaluate the role of PD-1, its ligands and IDO1 in a cohort of patients with primary diffuse large B-cell lymphoma of the CNS (PCNSL). Tissue microarrays (TMAs) were constructed in 45 PCNSL cases. RNA extraction from whole tissue sections and RNA sequencing were successfully p…

【数据结构与技术规格】

文件数 2 个，合计 118.48 KB。ionc_a_1881161_sm8345.docx：application/vnd.openxmlformats-officedocument.wordprocessingml.document，30.27 KB。ionc_a_1881161_sm8340.docx：application/vnd.openxmlformats-officedocument.wordprocessingml.document，88.21 KB。数据集 DOI：10.6084/m9.figshare.13979584.v1。

【主题与分类】

源站学科分类：Biophysics、Cell Biology、Molecular Biology、Immunology、Biological Sciences not elsewhere classified、Developmental Biology。主题标签：PCNSL、PD-1、PD-L1、PD-L2、IDO1、EBER。

【适用方向】

源站学科分类标注为 Biophysics、Cell Biology、Molecular Biology、Immunology、Biological Sciences not elsewhere classified、Developmental Biology。

【获取与许可】

源站页面：https://tandf.figshare.com/articles/dataset/PD-L1_and_IDO1_are_potential_targets_for_treatment_in_patients_with_primary_diffuse_large_B-cell_lymphoma_of_the_CNS/13979584

使用许可：CC BY 4.0（https://creativecommons.org/licenses/by/4.0/）。

规范引用：PD-L1 and IDO1 are potential targets for treatment in patients with primary diffuse large B-cell lymphoma of the CNS. Taylor & Francis. Abdulla, Maysaa; Alexsson, Andrei; Sundström, Christer; Ladenvall, Claes; Mansouri, Larry; Lindskog, Cecilia; et al

【使用注意】

· 源站最后修改于 2023-06-04，引用时请注意版本时效。