转移概率基础案例
膝骨关节炎Markov模型基础案例的转移概率数据,用于评估间充质干细胞和细胞外囊泡治疗的成本效果。

基本信息
资源简介
转移概率基础案例
【一句话概览】
本数据集是 figshare 公开的结构化表格数据集,收录 1 个文件、合计 5.63 KB,主题涵盖 mesenchymal stromal cells、manual production methods、improve mobility instead、conclusions persist among、total knee replacement,可用于统计建模、特征工程与队列分析,CC BY 4.0 许可开放获取。
【数据集背景】
本数据集源站标题为《Transition probabilities base-case.》。源站首次发布:2026-03-26。
【数据内容】
源站原始描述:Objectives Current osteoarthritis treatments are designed to reduce pain and improve mobility instead of promoting the regeneration of cartilage. Cell-based therapies are being developed for the treatment of osteoarthritis. The aim of this study was to assess the cost-effectiveness of mesenchymal stromal cells and extracellular vesicle treatments compared to standard of care for patients with Kellgren-Lawrence stage II knee osteoarthritis in the Netherlands, from a hospital and societal perspect…
【数据结构与技术规格】
文件数 1 个,合计 5.63 KB。Table 2.xls:application/vnd.ms-excel,5.63 KB。数据集 DOI:10.1371/journal.pone.0344203.t002。
【主题与分类】
源站学科分类:Cell Biology、Genetics、Pharmacology、Biotechnology、Ecology、Developmental Biology。主题标签:mesenchymal stromal cells、manual production methods、improve mobility instead、conclusions persist among、total knee replacement、way sensitivity analyses、year incremental cost、cell treatment groups、knee osteoarthritis patients、knee osteoarthritis。
【适用方向】
结构化表格数据可直接用于统计建模、特征工程与队列分析。
【获取与许可】
源站页面:https://plos.figshare.com/articles/dataset/_p_Transition_probabilities_base-case_p_/31862442
使用许可:CC BY 4.0(https://creativecommons.org/licenses/by/4.0/)。
规范引用:Boot, Iris W. A.; Shaw, Georgina; Ramos, Yolande F. M.; Murphy, Mary; Meulenbelt, Ingrid; Vrijhoef, Hubertus J. M. (2026). Transition probabilities base-case.. PLOS ONE. Dataset
下载信息
注册下载
需要注册 Kaggle 账号并登录后下载,适合需要跟踪下载记录和使用 API 的用户。
暂未开放公开下载
无需注册即可直接获取公开样本或文档,适合快速预览和评估数据集质量。
免登录当前数据集主要来源为 Kaggle 公开托管,完整影像包建议通过原始链接或 Kaggle API 获取。
使用方式
数据集获取(Figshare)
- 源站标题:<p>Transition probabilities base-case.</p>
- DOI:10.1371/journal.pone.0344203.t002
- 发布日期:2026-03-26
- 文件数:1 个
- 文件总体积:5.63 KB
- 源站页面:https://plos.figshare.com/articles/dataset/_p_Transition_probabilities_base-case_p_/31862442
命令行下载
curl -L -o "Table 2.xls" "https://ndownloader.figshare.com/files/63144105"
文件清单
Table 2.xls(5.63 KB)
文件总体积 5.63 KB(源站 API 实测)。
数据加载示例(图像类)
from PIL import Image
import glob, os
files = (glob.glob(os.path.join(path, "**", "*.png"), recursive=True)
+ glob.glob(os.path.join(path, "**", "*.jpg"), recursive=True)
+ glob.glob(os.path.join(path, "**", "*.tif"), recursive=True))
print("图像文件数:", len(files))
img = Image.open(files[0]); print("尺寸/模式:", img.size, img.mode)
# torchvision Dataset 方式:
# from torchvision import datasets
# ds = datasets.ImageFolder(path) # 要求 子目录=类别
目录组织与标注格式以源站说明和下载后实际文件为准。
数据说明
Objectives
Current osteoarthritis treatments are designed to reduce pain and improve mobility instead of promoting the regeneration of cartilage. Cell-based therapies are being developed for the treatment of osteoarthritis. The aim of this study was to assess the cost-effectiveness of mesenchymal stromal cells and extracellular vesicle treatments compared to standard of care for patients with Kellgren-Lawrence stage II knee osteoarthritis in the Netherlands, from a hospital and societal perspective.
Design
A Markov model was developed to assess the 40-year incremental cost-effectiveness ratio of mesenchymal stromal cells and/or extracellular vesicle treatments produced by automated or manual production methods, compared to standard of care. Secondary outcomes were amount of total knee replacement and total knee replacement revision surgeries. In addition, one-way sensitivity analyses and scenario analyses were performed.
Results
The incremental cost-effectiveness ratios from a hospital perspective were -€10,982.10 for automatically produced mesenchymal stromal cells, -€9,301.79 for manually produced mesenchymal stromal cells, -€12,793.17 for automatically produced mesenchymal stromal cells and extracellular vesicle, and -€11,998.02 for manually produced mesenchymal stromal cells and extracellular vesicle versus standard of care. From the societal perspective incremental cost-effectiveness ratios were €68,870.58 for automatically produced mesenchymal stromal cells, -€67,280.27 for manually produced mesenchymal stromal cells, -€70,771.65 for automatically produced mesenchymal stromal cells and extracellular vesicle, and -€69,976.50 for manually produced mesenchymal stromal cells and extracellular vesicle versus standard of care. The amount of total knee replacement surgeries per 1,000 patients was 426 for the cell treatment groups, and 609 for the standard of care group, and 19 and 30 total knee replacement revision surgeries, respectively.
Conclusions
This model, inherent to its assumptions, shows that hiMSC and EV treatments are cheaper and more effective for patients with knee osteoarthritis, from both perspectives. Moreover, they are expected to lower the numb
许可
CC BY 4.0
引用
学术使用请引用 DOI 10.1371/journal.pone.0344203.t002(source: https://plos.figshare.com/articles/dataset/_p_Transition_probabilities_base-case_p_/31862442)。
需要用于商业化训练或医疗器械注册(NMPA/FDA)?
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