在资源匮乏环境中使用结核病实验室信息系统减少沟通延迟并改善护理质量：一项集群随机对照试验

数据集获取（Figshare）

• 源站标题：Reducing Communication Delays and Improving Quality of Care with a Tuberculosis Laboratory Information System in Resource Poor Environments: A Cluster Randomized Controlled Trial
• DOI：10.1371/journal.pone.0090110
• 发布日期：2014-04-10
• 文件数：3 个
• 文件总体积：645.94 KB
• 源站页面：https://plos.figshare.com/articles/dataset/_Reducing_Communication_Delays_and_Improving_Quality_of_Care_with_a_Tuberculosis_Laboratory_Information_System_in_Resource_Poor_Environments_A_Cluster_Randomized_Controlled_Trial_/994690

命令行下载

curl -L -o "Checklist_S1.pdf" "https://ndownloader.figshare.com/files/1459060"
curl -L -o "Protocol_Secondary_Use_S1.pdf" "https://ndownloader.figshare.com/files/1459061"
curl -L -o "Procotol_Summary_S1.doc" "https://ndownloader.figshare.com/files/1459062"

文件清单

• Checklist_S1.pdf（422.20 KB）
• Protocol_Secondary_Use_S1.pdf（152.57 KB）
• Procotol_Summary_S1.doc（71.17 KB）

文件总体积 645.94 KB（源站 API 实测）。

数据说明

Background
Lost, delayed or incorrect laboratory results are associated with delays in initiating treatment. Delays in treatment for Multi-Drug Resistant Tuberculosis (MDR-TB) can worsen patient outcomes and increase transmission. The objective of this study was to evaluate the impact of a laboratory information system in reducing delays and the time for MDR-TB patients to culture convert (stop transmitting).
Methods
Setting: 78 primary Health Centers (HCs) in Lima, Peru. Participants lived within the catchment area of participating HCs and had at least one MDR-TB risk factor. The study design was a cluster randomized controlled trial with baseline data. The intervention was the e-Chasqui web-based laboratory information system. Main outcome measures were: times to communicate a result; to start or change a patient’'s treatment; and for that patient to culture convert.
Results
1671 patients were enrolled. Intervention HCs took significantly less time to receive drug susceptibility test (DST) (median 11 vs. 17 days, Hazard Ratio 0.67 [0.62–0.72]) and culture (5 vs. 8 days, 0.68 [0.65–0.72]) results. The time to treatment was not significantly different, but patients in intervention HCs took 16 days (20%) less time to culture convert (p = 0.047).
Conclusions
The eChasqui system reduced the time to communicate results between laboratories and HCs and time to culture conversion. It is now used in over 259 HCs covering 4.1 million people. This is the first randomized controlled trial of a laboratory information system in a developing country for any disease and the only study worldwide to show clinical impact of such a system.
Trial Registration
ClinicalTrials.gov NCT01201941

许可

CC BY 4.0

引用

学术使用请引用 DOI 10.1371/journal.pone.0090110（source: https://plos.figshare.com/articles/dataset/_Reducing_Communication_Delays_and_Improving_Quality_of_Care_with_a_Tuberculosis_Laboratory_Information_System_in_Resource_Poor_Environments_A_Cluster_Randomized_Controlled_Trial_/994690）。