中国耐多药结核病患者治疗前流失与延迟（2006-13）：规模与风险因素

数据集获取（Figshare）

• 源站标题：Attrition and delays before treatment initiation among patients with MDR-TB in China (2006-13): Magnitude and risk factors
• DOI：10.1371/journal.pone.0214943
• 发布日期：2019-04-08
• 文件数：2 个
• 文件总体积：14.33 MB
• 源站页面：https://plos.figshare.com/articles/dataset/Attrition_and_delays_before_treatment_initiation_among_patients_with_MDR-TB_in_China_2006-13_Magnitude_and_risk_factors/7965536

命令行下载

curl -L -o "pone.0214943.s001.tif" "https://ndownloader.figshare.com/files/14832443"
curl -L -o "pone.0214943.s002.xlsx" "https://ndownloader.figshare.com/files/14832446"

文件清单

• pone.0214943.s001.tif（1.51 MB）
• pone.0214943.s002.xlsx（12.82 MB）

文件总体积 14.33 MB（源站 API 实测）。

数据加载示例（图像类）

from PIL import Image
import glob, os

files = (glob.glob(os.path.join(path, "**", "*.png"), recursive=True)
       + glob.glob(os.path.join(path, "**", "*.jpg"), recursive=True)
       + glob.glob(os.path.join(path, "**", "*.tif"), recursive=True))
print("图像文件数:", len(files))
img = Image.open(files[0]); print("尺寸/模式:", img.size, img.mode)

# torchvision Dataset 方式:
# from torchvision import datasets
# ds = datasets.ImageFolder(path)  # 要求 子目录=类别

目录组织与标注格式以源站说明和下载后实际文件为准。

数据说明

Background
China’s national tuberculosis programme does not have cohort wise information regarding attrition and delays in the multidrug resistant tuberculosis (MDR-TB) diagnosis and treatment pathway.
Objective
Under the Global Fund programmatic management of drug-resistant TB (2006–13), we assessed the attrition and delay in the pathway and the factors associated.
Methods
Cohort study involving secondary programme data. All patients identified as presumptive MDR-TB (defined as i) previously treated TB patients which included recurrent TB, return after loss to follow up, treatment after failure and ii) new TB patients that were non-converters at three months of treatment or in close contact with a known MDR-TB patient) during October 2006 to June 2013 were eligible for phenotypic drug susceptibility testing (DST). Pre-diagnosis attrition (presumptive MDR-TB not undergoing culture and DST) and pre-treatment attrition (confirmed MDR-TB patients not initiated on treatment) was calculated. Diagnosis delay was the time interval from DST eligibility to DST result, treatment initiation delay was fom DST result to treatment initiation and total delay was from DST eligbility to treatment initiation. Factors associated with attrition and delay were identified using log binomial regression and linear regression, respectively.
Results
Of 78 564 presumptive MDR-TB patients, 2 470 (3.1%) underwent pre-diagnosis attrition. Of 9 283 MDR-TB patients, 3 361 (36.2%) underwent pre-treatment attrition. Median(IQR) diagnosis delay was 84 (64, 114) days; treatment initation delay was 23(6,68) days and total delay was 117(77,187) days. Long diagnosis delay was an independent predictor of pre-treatment attrition in a dose response relationship. While pre-treatment attrition was less likely among presumptive criterion ‘previously treated’ and with increasing time period, it was more likey among elderly and in east and west region. While the diagnosis delay increased with time period, treatment initiation delay and total delay reduced with time period. Short diagnosis delay was associated with west region, smear negative patients and presumptive criterion ‘treatment after lost to follow

许可

CC BY 4.0

引用

学术使用请引用 DOI 10.1371/journal.pone.0214943（source: https://plos.figshare.com/articles/dataset/Attrition_and_delays_before_treatment_initiation_among_patients_with_MDR-TB_in_China_2006-13_Magnitude_and_risk_factors/7965536）。