先天性弓形虫病新生儿筛查与产前筛查的成本效益分析数据集

数据集获取（Figshare）

• 源站标题：The cost-effectiveness of neonatal versus prenatal screening for congenital toxoplasmosis
• DOI：10.1371/journal.pone.0221709
• 发布日期：2019-09-18
• 文件数：5 个
• 文件总体积：2.52 MB
• 源站页面：https://plos.figshare.com/articles/dataset/The_cost-effectiveness_of_neonatal_versus_prenatal_screening_for_congenital_toxoplasmosis/9874958

命令行下载

curl -L -o "pone.0221709.s001.pdf" "https://ndownloader.figshare.com/files/17712548"
curl -L -o "pone.0221709.s002.pdf" "https://ndownloader.figshare.com/files/17712551"
curl -L -o "pone.0221709.s003.pdf" "https://ndownloader.figshare.com/files/17712557"
curl -L -o "pone.0221709.s004.pdf" "https://ndownloader.figshare.com/files/17712560"
curl -L -o "pone.0221709.s005.pdf" "https://ndownloader.figshare.com/files/17712563"

文件清单

• pone.0221709.s001.pdf（1.42 MB）
• pone.0221709.s002.pdf（228.21 KB）
• pone.0221709.s003.pdf（168.19 KB）
• pone.0221709.s004.pdf（317.25 KB）
• pone.0221709.s005.pdf（378.73 KB）

文件总体积 2.52 MB（源站 API 实测）。

数据加载示例（图像类）

from PIL import Image
import glob, os

files = (glob.glob(os.path.join(path, "**", "*.png"), recursive=True)
       + glob.glob(os.path.join(path, "**", "*.jpg"), recursive=True)
       + glob.glob(os.path.join(path, "**", "*.tif"), recursive=True))
print("图像文件数:", len(files))
img = Image.open(files[0]); print("尺寸/模式:", img.size, img.mode)

# torchvision Dataset 方式:
# from torchvision import datasets
# ds = datasets.ImageFolder(path)  # 要求 子目录=类别

目录组织与标注格式以源站说明和下载后实际文件为准。

数据说明

Background
Congenital Toxoplasmosis (CT) can have severe consequences. France, Austria, and Slovenia have prenatal screening programs whereas some other countries are considering universal screening to reduce congenital transmission and severity of infection in children. The efficiency of such programs is debated increasingly as seroprevalence among pregnant women and incidence of congenital toxoplasmosis show a steady decrease. In addition, uncertainty remains regarding the effectiveness of pre- and postnatal treatments.
Method
To identify cost-effective strategies, prenatal and neonatal screenings were compared using a decision-analytic model based on French guidelines and current knowledge of long-term evolution of the disease in treated children. Epidemiological data were extracted from the scientific literature and clinical data from the French Lyon cohort. Strategies were compared at one year of age, when infection can be definitively evaluated, and at 15 years of age, after which validated outcome data become scarce. The analysis was performed from the French Health Insurance System perspective and included direct medical costs for pregnant women and their children.
Results
The 1-year Incremental Cost-Effectiveness Ratio showed that prenatal screening would require investing €14,826 to avoid one adverse event (liveborn with CT, fetal loss, neonatal death or pregnancy termination) compared to neonatal screening. Extra investment increased up to €21,472 when considering the 15-year endpoint.
Conclusions
Prenatal screening is cost-effective as compared to neonatal screening in moderate prevalence areas with predominant Type II strains. In addition, prenatal screening, by providing closer follow-up of women at risk increases the number of occasions for education avoiding toxoplasmosis.

许可

CC BY 4.0

引用

学术使用请引用 DOI 10.1371/journal.pone.0221709（source: https://plos.figshare.com/articles/dataset/The_cost-effectiveness_of_neonatal_versus_prenatal_screening_for_congenital_toxoplasmosis/9874958）。