基于寡核苷酸微阵列可视化的奥司他韦与金刚烷胺耐药流感同步检测数据集

数据集获取（Figshare）

• 源站标题：Simultaneous Detection of Oseltamivir- and Amantadine-Resistant Influenza by Oligonucleotide Microarray Visualization
• DOI：10.1371/journal.pone.0057154
• 发布日期：2013-02-23
• 文件数：4 个
• 文件总体积：2.57 MB
• 源站页面：https://plos.figshare.com/articles/dataset/Simultaneous_Detection_of_Oseltamivir_and_Amantadine_Resistant_Influenza_by_Oligonucleotide_Microarray_Visualization__/638607

命令行下载

curl -L -o "Figure_S1.pdf" "https://ndownloader.figshare.com/files/969212"
curl -L -o "Figure_S2.pdf" "https://ndownloader.figshare.com/files/969217"
curl -L -o "Figure_S3.pdf" "https://ndownloader.figshare.com/files/969220"
curl -L -o "Figure_S4.pdf" "https://ndownloader.figshare.com/files/969223"

文件清单

• Figure_S1.pdf（129.37 KB）
• Figure_S2.pdf（100.68 KB）
• Figure_S3.pdf（227.66 KB）
• Figure_S4.pdf（2.12 MB）

文件总体积 2.57 MB（源站 API 实测）。

数据加载示例（图像类）

from PIL import Image
import glob, os

files = (glob.glob(os.path.join(path, "**", "*.png"), recursive=True)
       + glob.glob(os.path.join(path, "**", "*.jpg"), recursive=True)
       + glob.glob(os.path.join(path, "**", "*.tif"), recursive=True))
print("图像文件数:", len(files))
img = Image.open(files[0]); print("尺寸/模式:", img.size, img.mode)

# torchvision Dataset 方式:
# from torchvision import datasets
# ds = datasets.ImageFolder(path)  # 要求 子目录=类别

目录组织与标注格式以源站说明和下载后实际文件为准。

数据说明

Presently, the resistance of Influenza A virus isolates causes great difficulty for the prevention and treatment of influenza A virus infection. It is important to establish a drug-resistance detection method for epidemiological study and personalized medicine in the clinical setting. Consequently, a cost-effective oligonucleotide microarray visualization method, which was based on quantum dot-catalyzed silver deposition, was developed and evaluated for the simultaneous detection of neuraminidase H275Y and E119V; matrix protein 2 V27A and S31N mutations of influenza A (H3N2), seasonal influenza A (H1N1), and 2009 influenza A (H1N1). Then, 307 clinical throat swab specimens were detected and the drug-resistance results showed that 100% (17/17) of influenza A (H3N2) and 100% (259/259) of 2009 influenza A (H1N1) samples were resistant to amantadine and susceptible to oseltamivir; and 100% (5/5) of seasonal influenza A (H1N1) samples were resistant to both amantadine and oseltamivir.

许可

CC BY 4.0

引用

学术使用请引用 DOI 10.1371/journal.pone.0057154（source: https://plos.figshare.com/articles/dataset/Simultaneous_Detection_of_Oseltamivir_and_Amantadine_Resistant_Influenza_by_Oligonucleotide_Microarray_Visualization__/638607）。