巨噬细胞抑制烟曲霉萌发和中性粒细胞介导的真菌杀灭

资源简介

巨噬细胞抑制烟曲霉萌发和中性粒细胞介导的真菌杀灭

【数据集背景】

本数据集源站标题为《Macrophages inhibit Aspergillus fumigatus germination and neutrophil-mediated fungal killing》。配套论文《Macrophages inhibit Aspergillus fumigatus germination and neutrophil-mediated fungal killing》发表于 PLOS Pathogens（2018），DOI：10.1371/journal.ppat.1007229。源站首次发布：2018-08-02。

【数据内容】

源站原始描述：In immunocompromised individuals, Aspergillus fumigatus causes invasive fungal disease that is often difficult to treat. Exactly how immune mechanisms control A. fumigatus in immunocompetent individuals remains unclear. Here, we use transparent zebrafish larvae to visualize and quantify neutrophil and macrophage behaviors in response to different A. fumigatus strains. We find that macrophages form dense clusters around spores, establishing a protective niche for fungal survival. Macrophages exer…

【数据结构与技术规格】

文件数 10 个，合计 111.94 MB。数据集 DOI：10.1371/journal.ppat.1007229。

【主题与分类】

源站学科分类：Space Science、Microbiology、Physiology、Environmental Sciences not elsewhere classified、Ecology、Immunology。主题标签：Af 293-derived strain、CEA 10-derived strain、fumigatus strains、slower-growing Af 293-derived strains、Aspergillus fumigatus germination、CEA 10-derived strains、macrophage、Aspergillus fumigatus causes、CEA 10 pyrG。

【适用方向】

源站学科分类标注为 Space Science、Microbiology、Physiology、Environmental Sciences not elsewhere classified、Ecology、Immunology。

【获取与许可】

源站页面：https://plos.figshare.com/articles/dataset/Macrophages_inhibit_i_Aspergillus_fumigatus_i_germination_and_neutrophil-mediated_fungal_killing/6910004

使用许可：CC BY 4.0（https://creativecommons.org/licenses/by/4.0/）。

规范引用：E. Rosowski, Emily; Raffa, Nicholas; Knox, Benjamin P.; Golenberg, Netta; Keller, Nancy P.; Huttenlocher, Anna (2018). Macrophages inhibit Aspergillus fumigatus germination and neutrophil-mediated fungal killing. PLOS Pathogens. Dataset

【使用注意】

· 源站最后修改于 2023-06-01，引用时请注意版本时效。