BD FACSPresto™在埃塞俄比亚的CD4 T细胞计数、CD4%及血红蛋白浓度测试性能

数据集获取（Figshare）

• 源站标题：The performance of BD FACSPresto™ for CD4 T-cell count, CD4% and hemoglobin concentration test in Ethiopia
• DOI：10.1371/journal.pone.0176323
• 发布日期：2017-04-27
• 文件数：3 个
• 文件总体积：1.67 MB
• 源站页面：https://plos.figshare.com/articles/dataset/The_performance_of_BD_FACSPresto_for_CD4_T-cell_count_CD4_and_hemoglobin_concentration_test_in_Ethiopia/4926668

命令行下载

curl -L -o "S1 Fig.tif" "https://ndownloader.figshare.com/files/8322026"
curl -L -o "S1 Table.doc" "https://ndownloader.figshare.com/files/8322032"
curl -L -o "S1 Data.xls" "https://ndownloader.figshare.com/files/8322056"

文件清单

• S1 Fig.tif（1.55 MB）
• S1 Table.doc（31.74 KB）
• S1 Data.xls（87.04 KB）

文件总体积 1.67 MB（源站 API 实测）。

数据加载示例（图像类）

from PIL import Image
import glob, os

files = (glob.glob(os.path.join(path, "**", "*.png"), recursive=True)
       + glob.glob(os.path.join(path, "**", "*.jpg"), recursive=True)
       + glob.glob(os.path.join(path, "**", "*.tif"), recursive=True))
print("图像文件数:", len(files))
img = Image.open(files[0]); print("尺寸/模式:", img.size, img.mode)

# torchvision Dataset 方式:
# from torchvision import datasets
# ds = datasets.ImageFolder(path)  # 要求 子目录=类别

目录组织与标注格式以源站说明和下载后实际文件为准。

数据说明

Introduction
In Ethiopia, CD4+ T-cell counting is still required for all patients at baseline before antiretroviral therapy (ART) and to determine eligibility and follow-up of opportunistic infection prophylaxis. However, access to CD4+ T cell count in rural health facilities remains a major challenge in Ethiopia like other resource-limited settings.
Methodology
Both capillary and venous blood was drawn from each of 325 study participant recruited in Addis Ababa and surroundings. The CD4+ T-cell count, CD4%, and hemoglobin (Hgb) were tested at one of the four study health facilities using capillary blood and BD FACSPresto™ device. These tests were also done at the national HIV reference laboratory, using venous blood with BD FACSCalibur™, Sysmex XT-1800i™, and BD FACSPresto™.
Results
BD FACSPresto™ had an absolute mean bias of -13.3 cells/ul (-2.99%) and 28.3 cells/μl (6.4%) using venous and capillary blood, respectively, compared with BD FACSCalibur™. The absolute CD4 assay on the BD FACSPresto™ had a regression coefficient (R2) of 0.87 and 0.92 using capillary blood and venous blood samples, respectively, compared with BD FACSCalibur™. The percentage similarity of the BD FACSPresto™ using capillary and venous blood was 105.2% and 99.3%, respectively. The sensitivity of the FACSPresto™ using threshold of 500 cells/μl for ART eligibility using capillary and venous blood was 87.9 and 94.3%, while the specificity was 91.4 and 83.8%, respectively. Furthermore, the BD FACSPresto™ had an absolute mean bias of -0.2 dl/μl (0.0%) (95% LOA: -1.7, 1.3) and -0.59 dl/μl (0.1%) (95% LOA: -1.49, 0.31) for Hgb using capillary and venous blood compared with the Sysmex XT-1800i™, respectively.
Conclusion
Our results showed acceptable agreement between the BD FACSPresto™ and BD FACSCalibur™ for CD4+ T-cell counting and CD4%; and between the BD FACSPresto™ and Sysmex XT-1800i™for measuring Hgb concentration.

许可

CC BY 4.0

引用

学术使用请引用 DOI 10.1371/journal.pone.0176323（source: https://plos.figshare.com/articles/dataset/The_performance_of_BD_FACSPresto_for_CD4_T-cell_count_CD4_and_hemoglobin_concentration_test_in_Ethiopia/4926668）。