四状态马尔可夫模型参数输入

津巴布韦艾滋病青少年Zvandiri干预成本效益分析的Markov模型参数输入表格数据。

Figshare
2025-12-01 更新
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表格healthcare system perspectivedecreasing annual probabilityanalysis likely underestimatesvl )12reducing virological failurereduce virological failure99 per qalyml )10hiv transmissions resultingeffectiveness analysis extrapolating345 lys gained700 per ly
Four‐state Markov model parameter inputs.

基本信息

模态
表格
大小
0.000009728 GB
许可
CC BY 4.0
创建/更新时间
2025-12-01
版本
v1

资源简介

四状态马尔可夫模型参数输入

【数据集背景】

本数据集源站标题为《Four‐state Markov model parameter inputs.》。源站首次发布:2025-12-01。

【数据内容】

源站原始描述:Improving antiretroviral therapy (ART) adherence among adolescents living with HIV (ALHIV) improves outcomes, but with resource implications. We conducted a cost-effectiveness analysis extrapolating the costs and benefits of a community-based peer-support intervention (Zvandiri) among ALHIV in Zimbabwe. We used a de-novo multistate Markov decision-analytic model that simulated Zvandiri lifetime costs and benefits on viral suppression, death rates, life-years (LY) and quality-adjusted-life-years…

【数据结构与技术规格】

文件数 1 个,合计 9.73 KB。Table 2.xls:application/vnd.ms-excel,9.73 KB。数据集 DOI:10.1371/journal.pgph.0005545.t002。

【主题与分类】

源站学科分类:Medicine、Biological Sciences not elsewhere classified、Science Policy、Virology。主题标签:healthcare system perspective、decreasing annual probability、analysis likely underestimates、vl ), 12、reducing virological failure、reduce virological failure、99 per qaly、ml ), 10、hiv transmissions resulting、effectiveness analysis extrapolating。

【适用方向】

结构化表格数据可直接用于统计建模、特征工程与队列分析。

【获取与许可】

源站页面:https://plos.figshare.com/articles/dataset/Four_state_Markov_model_parameter_inputs_/30757390

使用许可:CC BY 4.0(https://creativecommons.org/licenses/by/4.0/)。

规范引用:Mangenah, Collin; Mavhu, Webster; Willis, Nicola; Mufuka, Juliet; Bernays, Sarah; Mangezi, Walter; et al. (2025). Four‐state Markov model parameter inputs.. PLOS Global Public Health. Dataset

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下载信息

注册下载

需要注册 Kaggle 账号并登录后下载,适合需要跟踪下载记录和使用 API 的用户。

暂未开放

公开下载

无需注册即可直接获取公开样本或文档,适合快速预览和评估数据集质量。

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有偿下载

公开数据集受托下载与技术交付服务。

提供高速下载与技术交付服务(收技术服务费,非数据销售)

暂未开放

当前数据集主要来源为 Kaggle 公开托管,完整影像包建议通过原始链接或 Kaggle API 获取。

使用方式

数据集获取(Figshare)

命令行下载

curl -L -o "Table 2.xls" "https://ndownloader.figshare.com/files/60013681"

文件清单

  • Table 2.xls(9.73 KB)

文件总体积 9.73 KB(源站 API 实测)。

数据加载示例(图像类)

from PIL import Image
import glob, os

files = (glob.glob(os.path.join(path, "**", "*.png"), recursive=True)
       + glob.glob(os.path.join(path, "**", "*.jpg"), recursive=True)
       + glob.glob(os.path.join(path, "**", "*.tif"), recursive=True))
print("图像文件数:", len(files))
img = Image.open(files[0]); print("尺寸/模式:", img.size, img.mode)

# torchvision Dataset 方式:
# from torchvision import datasets
# ds = datasets.ImageFolder(path)  # 要求 子目录=类别

目录组织与标注格式以源站说明和下载后实际文件为准。

数据说明

Improving antiretroviral therapy (ART) adherence among adolescents living with HIV (ALHIV) improves outcomes, but with resource implications. We conducted a cost-effectiveness analysis extrapolating the costs and benefits of a community-based peer-support intervention (Zvandiri) among ALHIV in Zimbabwe. We used a de-novo multistate Markov decision-analytic model that simulated Zvandiri lifetime costs and benefits on viral suppression, death rates, life-years (LY) and quality-adjusted-life-years (QALYs) gained from the healthcare system perspective. We estimate the incremental cost-effectiveness ratio (ICER) per LY and QALY gained and compare the ICER to proposed cost-effectiveness thresholds of $500 and $700 per LY or QALY gained. We explore parameter uncertainty using probabilistic sensitivity analyses. Cohort-microsimulation suggests that after 40 years under SoC, 21% of 280 ALHIV will have undetectable viral-load (VL), 12% will have low VL (<1000 copies/mL), 10% will have high VL (≥1000 copies/mL) and 57% would have died. With Zvandiri, ART adherence improves, decreasing annual probability of virological failure or death. After 40 years, 65% will have undetectable viral load, 23% low VL, 3% high VL and 9% would have died. Zvandiri results in 1,345 LYs gained at incremental cost of $500,587, yielding a discounted ICER of $372 per LY gained. Zvandiri also results in 1,246 QALYs at incremental cost of $123,645, yielding a discounted ICER of $99 per QALY. The ICER is highly sensitive to programme costs, health-related utilities, and the discount rate. Zvandiri is a cost-effective intervention for reducing virological failure and death in ALHIV. Our analysis likely underestimates the full benefits of the intervention by not accounting for reductions in HIV transmissions resulting from higher virological suppression observed in full transmission models.

许可

CC BY 4.0

引用

学术使用请引用 DOI 10.1371/journal.pgph.0005545.t002(source: https://plos.figshare.com/articles/dataset/Four_state_Markov_model_parameter_inputs_/30757390)。

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