HIV-1感染患者CD4监测频率决策规则数据集

数据集获取（Figshare）

• 源站标题：Development and Validation of Decision Rules to Guide Frequency of Monitoring CD4 Cell Count in HIV-1 Infection before Starting Antiretroviral Therapy
• DOI：10.1371/journal.pone.0018578
• 发布日期：2011-04-08
• 文件数：5 个
• 文件总体积：388.47 KB
• 源站页面：https://plos.figshare.com/articles/dataset/Development_and_Validation_of_Decision_Rules_to_Guide_Frequency_of_Monitoring_CD4_Cell_Count_in_HIV_1_Infection_before_Starting_Antiretroviral_Therapy/137643

命令行下载

curl -L -o "Figure_S1.tif" "https://ndownloader.figshare.com/files/393217"
curl -L -o "Appendix_S1.pdf" "https://ndownloader.figshare.com/files/393246"
curl -L -o "Appendix_S2.pdf" "https://ndownloader.figshare.com/files/393288"
curl -L -o "Excel_Tool_S1.xls" "https://ndownloader.figshare.com/files/393320"
curl -L -o "PRISMA_Flow_Diagram_S1.pdf" "https://ndownloader.figshare.com/files/393333"

文件清单

• Figure_S1.tif（94.54 KB）
• Appendix_S1.pdf（52.74 KB）
• Appendix_S2.pdf（60.83 KB）
• Excel_Tool_S1.xls（120.32 KB）
• PRISMA_Flow_Diagram_S1.pdf（60.05 KB）

文件总体积 388.47 KB（源站 API 实测）。

数据加载示例（图像类）

from PIL import Image
import glob, os

files = (glob.glob(os.path.join(path, "**", "*.png"), recursive=True)
       + glob.glob(os.path.join(path, "**", "*.jpg"), recursive=True)
       + glob.glob(os.path.join(path, "**", "*.tif"), recursive=True))
print("图像文件数:", len(files))
img = Image.open(files[0]); print("尺寸/模式:", img.size, img.mode)

# torchvision Dataset 方式:
# from torchvision import datasets
# ds = datasets.ImageFolder(path)  # 要求 子目录=类别

目录组织与标注格式以源站说明和下载后实际文件为准。

数据说明

Background
Although CD4 cell count monitoring is used to decide when to start antiretroviral therapy in patients with HIV-1 infection, there are no evidence-based recommendations regarding its optimal frequency. It is common practice to monitor every 3 to 6 months, often coupled with viral load monitoring. We developed rules to guide frequency of CD4 cell count monitoring in HIV infection before starting antiretroviral therapy, which we validated retrospectively in patients from the Swiss HIV Cohort Study.
Methodology/Principal Findings
We built up two prediction rules (“Snap-shot rule” for a single sample and “Track-shot rule” for multiple determinations) based on a systematic review of published longitudinal analyses of CD4 cell count trajectories. We applied the rules in 2608 untreated patients to classify their 18 061 CD4 counts as either justifiable or superfluous, according to their prior ≥5% or 6/L, respectively. The Track-shot rule was only marginally superior to the Snap-shot rule. Both rules lose usefulness for CD4 counts coming near to treatment threshold.
Conclusions/Significance
Frequent CD4 count monitoring of patients with CD4 counts well above the threshold for initiating therapy is unlikely to identify patients who require therapy. It appears sufficient to measure CD4 cell count 1 year after a count >650 for a threshold of 200, >900 for 350, or >1150 for 500×106/L, respectively. When CD4 counts fall below these limits, increased monitoring frequency becomes advisable. These rules offer guidance for efficient CD4 monitoring, particularly in resource-limited settings.

许可

CC BY 4.0

引用

学术使用请引用 DOI 10.1371/journal.pone.0018578（source: https://plos.figshare.com/articles/dataset/Development_and_Validation_of_Decision_Rules_to_Guide_Frequency_of_Monitoring_CD4_Cell_Count_in_HIV_1_Infection_before_Starting_Antiretroviral_Therapy/137643）。