HIV项目成本效果评估时间范围选择数据集

数据集获取（Figshare）

• 源站标题：Choice of time horizon critical in estimating costs and effects of changes to HIV programmes
• DOI：10.1371/journal.pone.0196480
• 发布日期：2018-05-16
• 文件数：2 个
• 文件总体积：623.16 KB
• 源站页面：https://plos.figshare.com/articles/dataset/Choice_of_time_horizon_critical_in_estimating_costs_and_effects_of_changes_to_HIV_programmes/6276587

命令行下载

curl -L -o "pone.0196480.s001.docx" "https://ndownloader.figshare.com/files/11484746"
curl -L -o "pone.0196480.s002.docx" "https://ndownloader.figshare.com/files/11484749"

文件清单

• pone.0196480.s001.docx（155.12 KB）
• pone.0196480.s002.docx（468.04 KB）

文件总体积 623.16 KB（源站 API 实测）。

数据加载示例（图像类）

from PIL import Image
import glob, os

files = (glob.glob(os.path.join(path, "**", "*.png"), recursive=True)
       + glob.glob(os.path.join(path, "**", "*.jpg"), recursive=True)
       + glob.glob(os.path.join(path, "**", "*.tif"), recursive=True))
print("图像文件数:", len(files))
img = Image.open(files[0]); print("尺寸/模式:", img.size, img.mode)

# torchvision Dataset 方式:
# from torchvision import datasets
# ds = datasets.ImageFolder(path)  # 要求 子目录=类别

目录组织与标注格式以源站说明和下载后实际文件为准。

数据说明

Background
Uganda changed its antiretroviral therapy guidelines in 2014, increasing the CD4 threshold for antiretroviral therapy initiation from 350 cells/μl to 500 cells/μl. We investigate what effect this change in policy is likely to have on HIV incidence, morbidity, and programme costs, and estimate the cost-effectiveness of the change over different time horizons.
Methods
We used a complex individual-based model of HIV transmission and antiretroviral therapy scale-up in Uganda. 100 model fits were generated by fitting the model to 51 demographic, sexual behaviour, and epidemiological calibration targets, varying 96 input parameters, using history matching with model emulation. An additional 19 cost and disability weight parameters were varied during the analysis of the model results. For each model fit, the model was run to 2030, with and without the change in threshold to 500 cells/μl.
Results
The change in threshold led to a 9.7% (90% plausible range: 4.3%-15.0%) reduction in incidence in 2030, and averted 278,944 (118,452–502,790) DALYs, at a total cost of $28M (-$142M to +$195M). The cost per disability adjusted life year (DALY) averted fell over time, from $3238 (-$125 to +$29,969) in 2014 to $100 (-$499 to +$785) in 2030. The change in threshold was cost-effective (cost Conclusions
Model results suggest that the change in threshold is unlikely to have been cost-effective to date, but is likely to be highly cost-effective in Uganda by 2030. The time horizon needs to be chosen carefully when projecting intervention effects. Large amounts of uncertainty in our results demonstrates the need to comprehensively incorporate uncertainties in model parameterisation.

许可

CC BY 4.0

引用

学术使用请引用 DOI 10.1371/journal.pone.0196480（source: https://plos.figshare.com/articles/dataset/Choice_of_time_horizon_critical_in_estimating_costs_and_effects_of_changes_to_HIV_programmes/6276587）。