VKA抗凝质量中心相关决定因素:前瞻性多中心评估

收录意大利292个中心83万余名VKA抗凝患者数据,分析中心管理因素对治疗质量(c-TTR)的影响,为优化抗凝监测提供依据。

Figshare
2016-02-23 更新
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表格anticoagulation clinicproactive strategiesr 2VKA therapypatient INRtarget INRVKA Anticoagulation Qualityregression modelEQA proficiency testinganticoagulant monitoringFCSACenter laboratory performance
Center-Related Determinants of VKA Anticoagulation Quality: A Prospective, Multicenter Evaluation

基本信息

模态
表格
大小
0.00012703 GB
许可
CC BY 4.0
创建/更新时间
2016-02-23
版本
v1

资源简介

VKA抗凝质量中心相关决定因素:前瞻性多中心评估

【数据集背景】

本数据集源站标题为《Center-Related Determinants of VKA Anticoagulation Quality: A Prospective, Multicenter Evaluation》。配套论文《Center-Related Determinants of VKA Anticoagulation Quality: A Prospective, Multicenter Evaluation》发表于 PLOS ONE(2015),DOI:10.1371/journal.pone.0144314。源站首次发布:2015-12-04。

【数据内容】

源站原始描述:Background Center-specific TTR (c-TTR) is a measure reporting the mean patient TTR within an anticoagulation clinic describing the quality of anticoagulant monitoring offered by that clinic. c-TTR has a considerable between-center variation, but its determinants are poorly understood. Objectives We aimed at evaluating which clinical, procedural or laboratory factors could be associated with c-TTR variability in a multicenter, observational cross-sectional study over a five-year period. Patients/…

【数据结构与技术规格】

文件数 2 个,合计 127.03 KB。S1 Appendix.docx:application/vnd.openxmlformats-officedocument.wordprocessingml.document,15.81 KB。S2 Appendix.zip:application/zip,111.22 KB。数据集 DOI:10.1371/journal.pone.0144314。

【主题与分类】

源站学科分类:Biochemistry、Medicine、Cell Biology、Molecular Biology、Neuroscience、Biotechnology。主题标签:anticoagulation clinic、proactive strategies、r 2、VKA therapy、patient INR、target INR、VKA Anticoagulation Quality、regression model、EQA proficiency testing、anticoagulant monitoring。

【适用方向】

结构化表格数据可直接用于统计建模、特征工程与队列分析。

【获取与许可】

源站页面:https://plos.figshare.com/articles/dataset/_Center_Related_Determinants_of_VKA_Anticoagulation_Quality_A_Prospective_Multicenter_Evaluation_/1618868

使用许可:CC BY 4.0(https://creativecommons.org/licenses/by/4.0/)。

规范引用:Tosetto, Alberto; Manotti, Cesare; Marongiu, Francesco (2016). Center-Related Determinants of VKA Anticoagulation Quality: A Prospective, Multicenter Evaluation. PLOS ONE. Dataset

【使用注意】

· 源站最后修改于 2023-06-06,引用时请注意版本时效。

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⚡️ 需要原始数据或标注支持?联系我们获取定制方案。

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下载信息

注册下载

需要注册 Kaggle 账号并登录后下载,适合需要跟踪下载记录和使用 API 的用户。

暂未开放

公开下载

无需注册即可直接获取公开样本或文档,适合快速预览和评估数据集质量。

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有偿下载

公开数据集受托下载与技术交付服务。

提供高速下载与技术交付服务(收技术服务费,非数据销售)

暂未开放

当前数据集主要来源为 Kaggle 公开托管,完整影像包建议通过原始链接或 Kaggle API 获取。

使用方式

数据集获取(Figshare)

命令行下载

curl -L -o "S1 Appendix.docx" "https://ndownloader.figshare.com/files/4308097"
curl -L -o "S2 Appendix.zip" "https://ndownloader.figshare.com/files/4308100"

文件清单

  • S1 Appendix.docx(15.81 KB)
  • S2 Appendix.zip(111.22 KB)

文件总体积 127.03 KB(源站 API 实测)。

数据加载示例(图像类)

from PIL import Image
import glob, os

files = (glob.glob(os.path.join(path, "**", "*.png"), recursive=True)
       + glob.glob(os.path.join(path, "**", "*.jpg"), recursive=True)
       + glob.glob(os.path.join(path, "**", "*.tif"), recursive=True))
print("图像文件数:", len(files))
img = Image.open(files[0]); print("尺寸/模式:", img.size, img.mode)

# torchvision Dataset 方式:
# from torchvision import datasets
# ds = datasets.ImageFolder(path)  # 要求 子目录=类别

目录组织与标注格式以源站说明和下载后实际文件为准。

数据说明

Background
Center-specific TTR (c-TTR) is a measure reporting the mean patient TTR within an anticoagulation clinic describing the quality of anticoagulant monitoring offered by that clinic. c-TTR has a considerable between-center variation, but its determinants are poorly understood.
Objectives
We aimed at evaluating which clinical, procedural or laboratory factors could be associated with c-TTR variability in a multicenter, observational cross-sectional study over a five-year period.
Patients/Methods
Data from 832,204 individual patients followed for VKA therapy in 292 Centers affiliated with the Italian Federation of Anticoagulation Clinics (FCSA) were analyzed. c-TTR was computed based on the TTR of patients followed at each Center, and a mixed linear regression model was used for a predefined set of explanatory variables.
Results
The Center next-visit interval ratio (the mean number of days after a visit with an INR outside the therapeutic range, divided by the days after a visit with an INR within the therapeutic range), the Center mean patient INR and the Center laboratory performance at EQA proficiency testing were the only variables that were independently associated with c-TTR (β-coefficients -17.32, 9.67, and -0.11, respectively; r2 = 0.635).
Conclusions
These findings suggest that c-TTR associates with proactive strategies aimed at keeping patients very close to their target INR with a prompt re-evaluation of those patients with under- or over-therapeutic INR.

许可

CC BY 4.0

引用

学术使用请引用 DOI 10.1371/journal.pone.0144314(source: https://plos.figshare.com/articles/dataset/_Center_Related_Determinants_of_VKA_Anticoagulation_Quality_A_Prospective_Multicenter_Evaluation_/1618868)。

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