全基因组分析揭示细胞外基质重塑、视觉周期和神经元发育在近视中的作用

资源简介

全基因组分析揭示细胞外基质重塑、视觉周期和神经元发育在近视中的作用

【数据集背景】

本数据集源站标题为《Genome-Wide Analysis Points to Roles for Extracellular Matrix Remodeling, the Visual Cycle, and Neuronal Development in Myopia》。配套论文《Genome-Wide Analysis Points to Roles for Extracellular Matrix Remodeling, the Visual Cycle, and Neuronal Development in Myopia》发表于 PLoS Genetics（2013），DOI：10.1371/journal.pgen.1003299。源站首次发布：2013-03-01。

【数据内容】

源站原始描述：Myopia, or nearsightedness, is the most common eye disorder, resulting primarily from excess elongation of the eye. The etiology of myopia, although known to be complex, is poorly understood. Here we report the largest ever genome-wide association study (45,771 participants) on myopia in Europeans. We performed a survival analysis on age of myopia onset and identified 22 significant associations (), two of which are replications of earlier associations with refractive error. Ten of the 20 novel…

【数据结构与技术规格】

文件数 6 个，合计 5.98 MB。Figure_S1.pdf：application/pdf，3.07 MB。Figure_S2.pdf：application/pdf，154.59 KB。Figure_S3.pdf：application/pdf，104.16 KB。数据集 DOI：10.1371/journal.pgen.1003299。

【主题与分类】

源站学科分类：Genetics、Medicine。主题标签：genome-wide、points、extracellular、matrix、neuronal、myopia。

【适用方向】

源站学科分类标注为 Genetics、Medicine。

【获取与许可】

源站页面：https://plos.figshare.com/articles/dataset/Genome_Wide_Analysis_Points_to_Roles_for_Extracellular_Matrix_Remodeling_the_Visual_Cycle_and_Neuronal_Development_in_Myopia__/641493

使用许可：CC BY 4.0（https://creativecommons.org/licenses/by/4.0/）。

规范引用：K. Kiefer, Amy; Y. Tung, Joyce; B. Do, Chuong; A. Hinds, David; L. Mountain, Joanna; Francke, Uta; et al. (2016). Genome-Wide Analysis Points to Roles for Extracellular Matrix Remodeling, the Visual Cycle, and Neuronal Development in Myopia. PLOS Genetics. Dataset

【使用注意】

· 源站最后修改于 2023-06-06，引用时请注意版本时效。