体重指数与近视关联：NHANES和孟德尔随机化结果

数据集获取（Figshare）

• 源站标题：Association Between Body Mass Index and Myopia: Results from NHANES and Mendelian Randomization
• DOI：10.6084/m9.figshare.28930451.v1
• 发布日期：2025-05-05
• 文件数：2 个
• 文件总体积：37.46 MB
• 源站页面：https://tandf.figshare.com/articles/dataset/Association_Between_Body_Mass_Index_and_Myopia_Results_from_NHANES_and_Mendelian_Randomization/28930451

命令行下载

curl -L -o "iope_a_2483684_sm9847.docx" "https://ndownloader.figshare.com/files/54194603"
curl -L -o "iope_a_2483684_sm9846.tif" "https://ndownloader.figshare.com/files/54194606"

文件清单

• iope_a_2483684_sm9847.docx（28.40 KB）
• iope_a_2483684_sm9846.tif（37.44 MB）

文件总体积 37.46 MB（源站 API 实测）。

数据加载示例（图像类）

from PIL import Image
import glob, os

files = (glob.glob(os.path.join(path, "**", "*.png"), recursive=True)
       + glob.glob(os.path.join(path, "**", "*.jpg"), recursive=True)
       + glob.glob(os.path.join(path, "**", "*.tif"), recursive=True))
print("图像文件数:", len(files))
img = Image.open(files[0]); print("尺寸/模式:", img.size, img.mode)

# torchvision Dataset 方式:
# from torchvision import datasets
# ds = datasets.ImageFolder(path)  # 要求 子目录=类别

目录组织与标注格式以源站说明和下载后实际文件为准。

数据说明

Purpose: Previous studies have shown a conflicting association between body mass index and myopia. This study aimed to analyze the possible association between Body Mass Index (BMI) and myopia in the observational design and genetic evidence.
Methods: In the observational investigation, 5,710 participants (12–25 years) from the 2001–2006 National Health and Nutrition Examination Survey (NHANES) were included. Weighted logistic regression models, restricted cubic spline (RCS) and stratified analysis were conducted in the NHANES. A two-sample Mendelian Randomization (MR) study using Genome-Wide Association Studies (GWAS) summary statistics and GWAS catalog was performed. The inverse-variance weighted (IVW) method was used as the main analysis method, and the sensitivity analysis was performed to detect pleiotropy and heterogeneity bias.
Results: In the fully adjusted model, individuals with obesity had a higher risk of myopia [OR = 1.253, 95% CI= (1.049, 1.496), p = 0.014] and mild and moderate myopia [OR = 1.305, 95% CI= (1.094, 1.558), p = 0.004]. BMI was correlated with refractive spherical equivalent and showed a linear relationship (P for nonlinearity = 0.468, p = 0.002,β=-0.016). In males, obesity had an association with myopia, while there was no statistical significance in females. In the subgroup with an education level of Conclusions: This study suggests that the associations between BMI and the risk of myopia differ based on gender and education levels in an observational study, while there are no associations in genetic evidence.

许可

CC BY 4.0

引用

学术使用请引用 DOI 10.6084/m9.figshare.28930451.v1（source: https://tandf.figshare.com/articles/dataset/Association_Between_Body_Mass_Index_and_Myopia_Results_from_NHANES_and_Mendelian_Randomization/28930451）。