赖氨酰氧化酶在多功能间充质细胞增殖中的新功能及其与炎症相关骨质减少的相关性

资源简介

赖氨酰氧化酶在多功能间充质细胞增殖中的新功能及其与炎症相关骨质减少的相关性

【数据集背景】

本数据集源站标题为《A Novel Function for Lysyl Oxidase in Pluripotent Mesenchymal Cell Proliferation and Relevance to Inflammation-Associated Osteopenia》。配套论文《A Novel Function for Lysyl Oxidase in Pluripotent Mesenchymal Cell Proliferation and Relevance to Inflammation-Associated Osteopenia》发表于 PLoS ONE（2014），DOI：10.1371/journal.pone.0100669。源站首次发布：2014-06-27。

【数据内容】

源站原始描述：Lysyl oxidase is a multifunctional enzyme required for collagen biosynthesis. Various growth factors regulate lysyl oxidase during osteoblast differentiation, subject to modulation by cytokines such as TNF-α in inflammatory osteopenic disorders including diabetic bone disease. Canonical Wnt signaling promotes osteoblast development. Here we investigated the effect of Wnt3a and TNF-α on lysyl oxidase expression in pluripotent C3H10T1/2 cells, bone marrow stromal cells, and committed osteoblasts.…

【数据结构与技术规格】

文件数 4 个，合计 1.33 MB。Figure_S1.tif：image/tiff，197.67 KB。Figure_S2.tif：image/tiff，194.60 KB。Figure_S3.tif：image/tiff，706.07 KB。数据集 DOI：10.1371/journal.pone.0100669。

【主题与分类】

源站学科分类：Biological Sciences。主题标签：anatomy、biological tissue、Connective tissue、bone、Connective tissue cells、Musculoskeletal system、cell biology、Cell processes、Cell growth、Cellular structures and organelles。

【适用方向】

源站学科分类标注为 Biological Sciences。

【获取与许可】

源站页面：https://plos.figshare.com/articles/dataset/_A_Novel_Function_for_Lysyl_Oxidase_in_Pluripotent_Mesenchymal_Cell_Proliferation_and_Relevance_to_Inflammation_Associated_Osteopenia_/1087672

使用许可：CC BY 4.0（https://creativecommons.org/licenses/by/4.0/）。

规范引用：Khosravi, Roozbeh; L. Sodek, Katharine; Xu, Wan-Peng; V. Bais, Manish; Saxena, Debashree; Faibish, Michael; et al. (2016). A Novel Function for Lysyl Oxidase in Pluripotent Mesenchymal Cell Proliferation and Relevance to Inflammation-Associated Osteopenia. PLOS ONE. Dataset

【使用注意】

· 源站最后修改于 2023-06-02，引用时请注意版本时效。