肥胖依赖性非酒精性脂肪肝病进展相关代谢特征

资源简介

肥胖依赖性非酒精性脂肪肝病进展相关代谢特征

【数据集背景】

本数据集源站标题为《Obesity-Dependent Metabolic

Signatures Associated with Nonalcoholic Fatty Liver Disease Progression》。配套论文《Obesity-Dependent Metabolic Signatures Associated with Nonalcoholic Fatty Liver Disease Progression》发表于 Journal of Proteome Research（2012），DOI：10.1021/pr201223p。源站首次发布：2016-02-21。

【数据内容】

源站原始描述：Our understanding of the mechanisms by which nonalcoholic fatty liver disease (NAFLD) progresses from simple steatosis to steatohepatitis (NASH) is still very limited. Despite the growing number of studies linking the disease with altered serum metabolite levels, an obstacle to the development of metabolome-based NAFLD predictors has been the lack of large cohort data from biopsy-proven patients matched for key metabolic features such as obesity. We studied 467 biopsied individuals with normal l…

【数据结构与技术规格】

文件数 1 个，合计 443.39 KB。pr201223p_si_006.xls：application/vnd.ms-excel，443.39 KB。数据集 DOI：10.1021/pr201223p.s006。

【主题与分类】

源站学科分类：Biochemistry、Medicine、Genetics、Physiology、Biotechnology、Chemical Sciences not elsewhere classified。主题标签：Qualitative determinations、cohort data、NASH biomarkers、540 serum metabolite variables、mass spectrometry、BMI、NAFLD serum、UPLC、validation group、Nonalcoholic Fatty Liver Disease ProgressionOur understanding。

【适用方向】

源站学科分类标注为 Biochemistry、Medicine、Genetics、Physiology、Biotechnology、Chemical Sciences not elsewhere classified。

【获取与许可】

源站页面：https://acs.figshare.com/articles/dataset/Obesity_Dependent_Metabolic_Signatures_Associated_with_Nonalcoholic_Fatty_Liver_Disease_Progression/2534290

使用许可：CC BY-NC 4.0（https://creativecommons.org/licenses/by-nc/4.0/）。

规范引用：Barr, J.; Caballería, J.; Martínez-Arranz, I.; Domínguez-Díez, A.; Alonso, C.; Muntané, J.; et al. (2016). Obesity-Dependent Metabolic Signatures Associated with Nonalcoholic Fatty Liver Disease Progression. ACS Publications. Dataset

【使用注意】

· 源站最后修改于 2023-06-07，引用时请注意版本时效。