治疗质量指标能否预测糖尿病患者的心血管结局？

数据集获取（Figshare）

• 源站标题：Do Treatment Quality Indicators Predict Cardiovascular Outcomes in Patients with Diabetes?
• DOI：10.1371/journal.pone.0078821
• 发布日期：2013-10-30
• 文件数：4 个
• 文件总体积：136.14 KB
• 源站页面：https://plos.figshare.com/articles/dataset/_Do_Treatment_Quality_Indicators_Predict_Cardiovascular_Outcomes_in_Patients_with_Diabetes_/836022

命令行下载

curl -L -o "Table_S1.docx" "https://ndownloader.figshare.com/files/1261615"
curl -L -o "Table_S2.docx" "https://ndownloader.figshare.com/files/1261616"
curl -L -o "Table_S3.docx" "https://ndownloader.figshare.com/files/1261617"
curl -L -o "Table_S4.docx" "https://ndownloader.figshare.com/files/1261618"

文件清单

• Table_S1.docx（27.25 KB）
• Table_S2.docx（29.93 KB）
• Table_S3.docx（27.06 KB）
• Table_S4.docx（51.91 KB）

文件总体积 136.14 KB（源站 API 实测）。

数据加载示例（图像类）

from PIL import Image
import glob, os

files = (glob.glob(os.path.join(path, "**", "*.png"), recursive=True)
       + glob.glob(os.path.join(path, "**", "*.jpg"), recursive=True)
       + glob.glob(os.path.join(path, "**", "*.tif"), recursive=True))
print("图像文件数:", len(files))
img = Image.open(files[0]); print("尺寸/模式:", img.size, img.mode)

# torchvision Dataset 方式:
# from torchvision import datasets
# ds = datasets.ImageFolder(path)  # 要求 子目录=类别

目录组织与标注格式以源站说明和下载后实际文件为准。

数据说明

Background
Landmark clinical trials have led to optimal treatment recommendations for patients with diabetes. Whether optimal treatment is actually delivered in practice is even more important than the efficacy of the drugs tested in trials. To this end, treatment quality indicators have been developed and tested against intermediate outcomes. No studies have tested whether these treatment quality indicators also predict hard patient outcomes.
Methods
A cohort study was conducted using data collected from >10.000 diabetes patients in the Groningen Initiative to Analyze Type 2 Treatment (GIANTT) database and Dutch Hospital Data register. Included quality indicators measured glucose-, lipid-, blood pressure- and albuminuria-lowering treatment status and treatment intensification. Hard patient outcome was the composite of cardiovascular events and all-cause death. Associations were tested using Cox regression adjusting for confounding, reporting hazard ratios (HR) with 95% confidence intervals.
Results
Lipid and albuminuria treatment status, but not blood pressure lowering treatment status, were associated with the composite outcome (HR = 0.77, 0.67–0.88; HR = 0.75, 0.59–0.94). Glucose lowering treatment status was associated with the composite outcome only in patients with an elevated HbA1c level (HR = 0.72, 0.56–0.93). Treatment intensification with glucose-lowering but not with lipid-, blood pressure- and albuminuria-lowering drugs was associated with the outcome (HR = 0.73, 0.60–0.89).
Conclusion
Treatment quality indicators measuring lipid- and albuminuria-lowering treatment status are valid quality measures, since they predict a lower risk of cardiovascular events and mortality in patients with diabetes. The quality indicators for glucose-lowering treatment should only be used for restricted populations with elevated HbA1c levels. Intriguingly, the tested indicators for blood pressure-lowering treatment did not predict patient outcomes. These results question whether all treatment indicators are valid measures to judge quality of health care and its economics.

许可

CC BY 4.0

引用

学术使用请引用 DOI 10.1371/journal.pone.0078821（source: https://plos.figshare.com/articles/dataset/_Do_Treatment_Quality_Indicators_Predict_Cardiovascular_Outcomes_in_Patients_with_Diabetes_/836022）。