临界深度拉曼光谱实现家用非侵入式血糖监测

数据集获取（Figshare）

• 源站标题：Critical-depth Raman spectroscopy enables home-use non-invasive glucose monitoring
• DOI：10.1371/journal.pone.0197134
• 发布日期：2018-05-11
• 文件数：5 个
• 文件总体积：38.54 MB
• 源站页面：https://plos.figshare.com/articles/dataset/Critical-depth_Raman_spectroscopy_enables_home-use_non-invasive_glucose_monitoring/6261386

命令行下载

curl -L -o "pone.0197134.s001.tif" "https://ndownloader.figshare.com/files/11443136"
curl -L -o "pone.0197134.s002.tif" "https://ndownloader.figshare.com/files/11443139"
curl -L -o "pone.0197134.s003.pdf" "https://ndownloader.figshare.com/files/11443145"
curl -L -o "pone.0197134.s004.pdf" "https://ndownloader.figshare.com/files/11443148"
curl -L -o "pone.0197134.s005.mat" "https://ndownloader.figshare.com/files/11443151"

文件清单

• pone.0197134.s001.tif（4.05 MB）
• pone.0197134.s002.tif（3.52 MB）
• pone.0197134.s003.pdf（117.07 KB）
• pone.0197134.s004.pdf（146.82 KB）
• pone.0197134.s005.mat（30.70 MB）

文件总体积 38.54 MB（源站 API 实测）。

数据加载示例（图像类）

from PIL import Image
import glob, os

files = (glob.glob(os.path.join(path, "**", "*.png"), recursive=True)
       + glob.glob(os.path.join(path, "**", "*.jpg"), recursive=True)
       + glob.glob(os.path.join(path, "**", "*.tif"), recursive=True))
print("图像文件数:", len(files))
img = Image.open(files[0]); print("尺寸/模式:", img.size, img.mode)

# torchvision Dataset 方式:
# from torchvision import datasets
# ds = datasets.ImageFolder(path)  # 要求 子目录=类别

目录组织与标注格式以源站说明和下载后实际文件为准。

数据说明

One of the most ambitious endeavors in the field of diabetes technology is non-invasive glucose sensing. In the past decades, a number of different technologies have been assessed, but none of these have found its entry into general clinical use. We report on the development of a table-top confocal Raman spectrometer that was used in the home of patients with diabetes and operated for extended periods of time unsupervised and without recalibration. The system is based on measurement of glucose levels at a ‘critical depth’ in the skin, specifically in the interstitial fluid located below the stratum corneum but above the underlying adipose tissue layer. The region chosen for routine glucose measurements was the base of the thumb (the thenar). In a small clinical study, 35 patients with diabetes analyzed their interstitial fluid glucose for a period of 60 days using the new critical-depth Raman (CD-Raman) method and levels were correlated to reference capillary blood glucose values using a standard finger-stick and test strip product. The calibration of the CD-Raman system was stable for > 10 days. Measurement performance for glucose levels present at, or below, a depth of ~250μm below the skin surface was comparable to that reported for currently available invasive continuous glucose monitors. In summary, using the CD-Raman technology we have demonstrated the first successful use of a non-invasive glucose monitor in the home.

许可

CC BY 4.0

引用

学术使用请引用 DOI 10.1371/journal.pone.0197134（source: https://plos.figshare.com/articles/dataset/Critical-depth_Raman_spectroscopy_enables_home-use_non-invasive_glucose_monitoring/6261386）。