肢端肥大症患者脂肪组织基因表达特征数据集

资源简介

肢端肥大症患者脂肪组织基因表达特征数据集

【数据集背景】

本数据集源站标题为《Gene Expression Signature in Adipose Tissue of Acromegaly Patients》。配套论文《Gene Expression Signature in Adipose Tissue of Acromegaly Patients》发表于 PLOS ONE（2015），DOI：10.1371/journal.pone.0129359。源站首次发布：2015-06-18。

【数据内容】

源站原始描述：To study the effect of chronic excess growth hormone on adipose tissue, we performed RNA sequencing in adipose tissue biopsies from patients with acromegaly (n = 7) or non-functioning pituitary adenomas (n = 11). The patients underwent clinical and metabolic profiling including assessment of HOMA-IR. Explants of adipose tissue were assayed ex vivo for lipolysis and ceramide levels. Patients with acromegaly had higher glucose, higher insulin levels and higher HOMA-IR score. We observed several pr…

【数据结构与技术规格】

文件数 8 个，合计 14.02 MB。S1_Fig.tif：image/tiff，165.58 KB。S2_Fig.tif：image/tiff，323.91 KB。S3_Fig.tif：image/tiff，176.60 KB。数据集 DOI：10.1371/journal.pone.0129359。

【主题与分类】

源站学科分类：Biological Sciences。主题标签：fads、NRIP、tcf、lpl、gh、ABHD、scd、gene expression signature、igf、adipose tissue lipolysis。

【适用方向】

源站学科分类标注为 Biological Sciences。

【获取与许可】

源站页面：https://plos.figshare.com/articles/dataset/_Gene_Expression_Signature_in_Adipose_Tissue_of_Acromegaly_Patients_/1453979

使用许可：CC BY 4.0（https://creativecommons.org/licenses/by/4.0/）。

规范引用：Hochberg, Irit; T. Tran, Quynh; L. Barkan, Ariel; R. Saltiel, Alan; F. Chandler, William; Bridges, Dave (2016). Gene Expression Signature in Adipose Tissue of Acromegaly Patients. PLOS ONE. Dataset

【使用注意】

· 源站最后修改于 2023-06-11，引用时请注意版本时效。