肢端肥大症中端粒加速缩短；IGF-I诱导端粒缩短和细胞衰老

资源简介

肢端肥大症中端粒加速缩短；IGF-I诱导端粒缩短和细胞衰老

【数据集背景】

本数据集源站标题为《Accelerated Telomere Shortening in Acromegaly; IGF-I Induces Telomere Shortening and Cellular Senescence》。配套论文《Accelerated Telomere Shortening in Acromegaly; IGF-I Induces Telomere Shortening and Cellular Senescence》发表于 PLOS ONE（2015），DOI：10.1371/journal.pone.0140189。源站首次发布：2015-10-08。

【数据内容】

源站原始描述：Objective Patients with acromegaly exhibit reduced life expectancy and increased prevalence of age-related diseases, such as diabetes, hypertension, and cardiovascular disease. However, the underlying mechanism has not been fully elucidated. Telomere shortening is reportedly associated with reduced life expectancy and increased prevalence of these age-related diseases. Methods We measured telomere length in patients with acromegaly using quantitative PCR method. The effect of GH and IGF-I on tel…

【数据结构与技术规格】

文件数 6 个，合计 2.25 MB。S1_Fig.tif：image/tiff，985.20 KB。S2_Fig.tif：image/tiff，333.11 KB。S3_Fig.tif：image/tiff，437.00 KB。数据集 DOI：10.1371/journal.pone.0140189。

【主题与分类】

源站学科分类：Biological Sciences。主题标签：telomere、gh、pcr、telomere length、Cellular Senescence ObjectivePatients、acromegaly、p 21 protein、life expectancy。

【适用方向】

源站学科分类标注为 Biological Sciences。

【获取与许可】

源站页面：https://plos.figshare.com/articles/dataset/_Accelerated_Telomere_Shortening_in_Acromegaly_IGF_I_Induces_Telomere_Shortening_and_Cellular_Senescence_/1570427

使用许可：CC BY 4.0（https://creativecommons.org/licenses/by/4.0/）。

规范引用：Matsumoto, Ryusaku; Fukuoka, Hidenori; Iguchi, Genzo; Odake, Yukiko; Yoshida, Kenichi; Bando, Hironori; et al. (2016). Accelerated Telomere Shortening in Acromegaly; IGF-I Induces Telomere Shortening and Cellular Senescence. PLOS ONE. Dataset

【使用注意】

· 源站最后修改于 2023-05-31，引用时请注意版本时效。