HIV Nef蛋白向血管内皮转移导致内皮功能障碍

资源简介

HIV Nef蛋白向血管内皮转移导致内皮功能障碍

【数据集背景】

本数据集源站标题为《Transfer of Intracellular HIV Nef to Endothelium Causes Endothelial Dysfunction》。配套论文《Transfer of Intracellular HIV Nef to Endothelium Causes Endothelial Dysfunction》发表于 PLoS ONE（2014），DOI：10.1371/journal.pone.0091063。源站首次发布：2014-03-07。

【数据内容】

源站原始描述：With effective antiretroviral therapy (ART), cardiovascular diseases (CVD) are emerging as a major cause of morbidity and death in the aging HIV-infected population. To address whether HIV-Nef, a viral protein produced in infected cells even when virus production is halted by ART, can lead to endothelial activation and dysfunction, we tested Nef protein transfer to and activity in endothelial cells. We demonstrated that Nef is essential for major endothelial cell activating effects of HIV-infect…

【数据结构与技术规格】

文件数 3 个，合计 432.02 KB。Figure_S1.tif：image/tiff，97.90 KB。Figure_S2.tif：image/tiff，190.35 KB。Figure_S3.tif：image/tiff，143.77 KB。数据集 DOI：10.1371/journal.pone.0091063。

【主题与分类】

源站学科分类：Biological Sciences、Medicine。主题标签：immunology、Immune cells、t cells、microbiology、Virology、Viral enzymes、Molecular cell biology、Cellular types、Endothelial cells、Cell death。

【适用方向】

源站学科分类标注为 Biological Sciences、Medicine。

【获取与许可】

源站页面：https://plos.figshare.com/articles/dataset/_Transfer_of_Intracellular_HIV_Nef_to_Endothelium_Causes_Endothelial_Dysfunction_/955682

使用许可：CC BY 4.0（https://creativecommons.org/licenses/by/4.0/）。

规范引用：Wang, Ting; A. Green, Linden; K. Gupta, Samir; Kim, Chul; Wang, Liang; Almodovar, Sharilyn; et al. (2016). Transfer of Intracellular HIV Nef to Endothelium Causes Endothelial Dysfunction. PLOS ONE. Dataset

【使用注意】

· 源站最后修改于 2023-06-09，引用时请注意版本时效。