爱尔兰狼犬扩张型心肌病多基因位点关联数据集

资源简介

爱尔兰狼犬扩张型心肌病多基因位点关联数据集

【数据集背景】

本数据集源站标题为《Multiple Loci Are Associated with Dilated Cardiomyopathy in Irish Wolfhounds》。配套论文《Multiple Loci Are Associated with Dilated Cardiomyopathy in Irish Wolfhounds》发表于 PLoS ONE（2012），DOI：10.1371/journal.pone.0036691。源站首次发布：2012-06-25。

【数据内容】

源站原始描述：Dilated cardiomyopathy (DCM) is a highly prevalent and often lethal disease in Irish wolfhounds. Complex segregation analysis indicated different loci involved in pathogenesis. Linear fixed and mixed models were used for the genome-wide association study. Using 106 DCM cases and 84 controls we identified one SNP significantly associated with DCM on CFA37 and five SNPs suggestively associated with DCM on CFA1, 10, 15, 21 and 17. On CFA37 MOGAT1 and ACSL3 two enzymes of the lipid metabolism were l…

【数据结构与技术规格】

文件数 11 个，合计 11.18 MB。Figure_S1.tif：image/tiff，1.00 MB。Figure_S2.tif：image/tiff，698.62 KB。Figure_S3.tif：image/tiff，2.81 MB。数据集 DOI：10.1371/journal.pone.0036691。

【主题与分类】

源站学科分类：Genetics。主题标签：loci、are、dilated、cardiomyopathy、irish、wolfhounds。

【适用方向】

源站学科分类标注为 Genetics。

【获取与许可】

源站页面：https://plos.figshare.com/articles/dataset/Multiple_Loci_Are_Associated_with_Dilated_Cardiomyopathy_in_Irish_Wolfhounds/123547

使用许可：CC BY 4.0（https://creativecommons.org/licenses/by/4.0/）。

规范引用：Philipp, Ute; Vollmar, Andrea; Häggström, Jens; Thomas, Anne; Distl, Ottmar (2016). Multiple Loci Are Associated with Dilated Cardiomyopathy in Irish Wolfhounds. PLOS ONE. Dataset

【使用注意】

· 源站最后修改于 2023-05-31，引用时请注意版本时效。